New insights into centromere structure [W[R]C]
Researchers led by Osaka University used cryogenic electron microscopy to analyze the atomic structure of the centromeric region of the chromosome, essential for cell division. A protein called CENP-A marks the centromere; the researchers showed that during interphase, CENP-A is bound by a protein called KNL2 to maintain the location of the centromere. During mitosis, KNL2 is replaced by CENP-C, allowing correct formation of the kinetochore complex for cell division.
Sponsored by The BlogDealer – Health, Fitness and Fat Reduction.
Listen to “New insights into centromere structure [W[R]C]” on Spreaker.
